Angiosarcoma Stewart-Treves Occurs 10-20 years after radical mastectomy in the edematous skin of the upper extremity. The origin (lymphatic or vascular) is not known. Histologically often very cellular, with small slit-like vascular spaces. Positive for common endothelial cell markers.
Angiosarcoma Stewart-Treves
Post-irradiation angiosarcoma Angiosarcoma can manifest in the breast after conservative surgery or in the chest wall after mastectomy when post-operative radiotherapy has been given to the patient. The mean latency time is 5-6 years. Post-irradiation angiosarcoma involves skin in most cases. The tumors are often multifocal. Morphologically the tumor is a grade II-III angiosarcoma, and associated with a poor prognosis of the patient.
Post-irradiation angiosarcoma
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