Background
The Gleason grading system is the most widely used
and accepted
grading
system for prostatic adenocar-
cinoma. The Gleason grade of a prostate
needle
biopsy can have important clinical implications, and
to
ensure objective
therapeutic decisions, grading
should be as accurate and
uniform
as
possible.
The Gleason grading system is based on evalua-
ting the architectural
pattern
of the malignant glands
observed at a relatively low magnification.
The two
most prevalent patterns are assigned grades from 1
to 5, with 1 being the
most differentiated and 5 the least
differentiated. The sum of the
two grades,
called the
Gleason score, thus obtains values from 2 to 10. |
Schematic Gleason diagram
appearing at the
site by
Lars Egevad, Karolinska Hospital
|
background
