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21st European Congress of Pathology
Istanbul, Turkey, September 08-13, 2007
http://www.ecp2007istanbul.org/
ESP/IAP Joint Meeting:
Debates on the Diagnosis of Selected Lymphoproliferative Disorders, September 10th
 Chairpersons: K. Henry and G. Kontogeorgos
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Case 1
Presented by: Prof. Bharat Nathwani,
University of Southern California, Keck School of Medicine

Clinical History
This 2-year-old healthy, asymptomatic boy developed progressive generalized lymphadenopathy and hepatosplenomegaly over 18 months.

Labs: WBC 14.8; Hgb 11.1; Plt Normal; IgG 2300 (400-1000); IgA 158 (14-122); IgM 213 (47-60)



Only snapshots available
  

 Diagnosis & discussion
Case 2
Presented by: Prof. Bharat Nathwani,
University of Southern California, Keck School of Medicine

Clinical History
17-year-old female had right tonsillectomy for tonsillar enlargement.



Only snapshots available
  

 Diagnosis & discussion
Case 3
Presented by: Prof. CJLM Meijer,
VU University Medical Center, Amsterdam, The Netherlands

Patient: Female, 70 years

Presentation: Since 5 months growing nodule on the lower back left. 3 months later nodule medial on the left upper leg. No other complaints. (Appendectomy, TIA, hysterectomy, hypertension.

Medication: Atenolol, Dytenzide, Paroxetide

Localisation: Bilobular, red, strongly infiltrated tumor on the lower back left, Ø 9x6,7cm. Strongly elevated red nodule on the left upper leg, close to the groin, Ø 2x2 cm.

Staging: No palpable lymphnode present. Leuco’s/leucodiff: normal. IgM-kappa paraprotein. CT-scan head/neck, thorax, abdomen: no extra cutaneous localisation. Crista biopsy: no lymphoma localisation.




Only snapshots available
  

 Diagnosis & discussion
Case 4
Presented by: Prof. CJLM Meijer,
VU University Medical Center, Amsterdam, The Netherlands

Patient: Female, 22 years

Presentation: Since 3 months solitary tumor on forehead. Solitary nodules in front of the left ear. No other skinlesions. Lymph nodes not enlarged.

Staging: CT-scans, bone marrow: no involvement



Only snapshots available
  

 Diagnosis & discussion
Case 5
Presented by: Prof. Ahmet Dogan,
Mayo Clinic, Rochester MN 55905

Clinical History
54 year old male. Cervical, axillary and mediastinal lymphadenopathy and pleural effusion. Axillary lymph node biopsy.



Only snapshots available
  

 Diagnosis & discussion
Case 6
Presented by: Prof. Ahmet Dogan,
Mayo Clinic, Rochester MN 55905

Clinical History
72 year old female. Generalized lymphadenopathy, hepatosplenomegaly and skin rash. Inguinal lymph node biopsy.



Only snapshots available
  
Case 7
Presented by: Prof. Kristin Henry,
Imperial College London,
Charing Cross Hospital

Clinical data
Man aged 25 yrs. Presented with painful ulcerated perianal nodules.

Pre biopsy diagnosis? Crohns disease

Figs 1-6 Representative views of histological features



Only snapshots available
  

 Diagnosis & discussion
Case 8
Presented by: Prof. Kristin Henry,
Imperial College London,
Charing Cross Hospital

Clinical data
Man aged 32 years. Developed 2 hard lumps in skin of upper arm. No lymph node enlargement or other abnormal findings.

Initial diagnosis insect bites.

Figs. 1-6 Histologic features



Only snapshots available
  

 Diagnosis & discussion


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