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21st European Congress of Pathology
Istanbul, Turkey, September 08-13, 2007
http://www.ecp2007istanbul.org/
Slide Seminar 16, September 13th
The Marriage Between Morphology and Genetics in Soft Tissue Tumors
Chairperson: R. Sciot |
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Case 1
Presented by: Dr. J. Bovee
Clinical History
52-year-old male. Farmer, coughing complaints. On conventional chest X-ray: miliary features. Open lung biopsies were taken.
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Diagnosis & discussion |
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Case 2
Presented by: D. C. Kuhnen
Clinical History
A 15-year-old boy presented with a 7cm cystic lesion in the upper left abdomen. The lesion had been detected by ultrasound on occasion following a traumatic event. Additional smaller solid tumor nodules surrounded the cystic process nearby and apparently represented tumor dissemination. Tumor resection was performed under the suspicion of a malignant tumor.
Macroscopic findings:The resetion specimen included a cystic area measuring 7x5x4 cm excised from the ligamentum gastrocolicum. Two additional tumor nodules up to approx. 3,5cm located nearby were resected apart from several smaller nodules up to 1, cm which were found within the greater omentum. The cystic area filled with partly hemorrhagic fluid, the solid nodules showed a white, firm cut surface.
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Diagnosis & discussion |
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Case 3
Presented by: Dr. SF Grazio
Clinical History
A 49-year-old woman with neurofibromatosis type I diagnosed in childhood and history of several operations underwent an excision of a recurrent mass in the right sacrogluteal region The surgical specimen, which consisted of skin subcutaneous tissue and muscle, measured 12x10x7 cm and showed an ill-defined subcutaneous tumor measuring 9x6x4 cm, with a glistening, yellowish-gray cut surface
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Diagnosis & discussion |
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Case 4
Presented by: Dr. A. L. Folpe
Clinical History
12 year-old male with a long standing mass of the superfical soft itssues on the left thigh, thought clinically to represent an old hematoma secondary to sport- related trauma.
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Diagnosis & discussion |
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Case 5
Presented by: Dr. C. Gengler
Clinical History
A 62-year-old male presenting with a mass in the right thigh. The mass is deep-seated and measures 13x6 cm.
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Diagnosis & discussion |
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Case 6
Presented by: Dr. K. Cooper
Clinical History
This is a 59-year-old woman who presented with apelvic ass. The hysterectomy specimen demonstrated a massive uterine tumor ( 15x10x1,5cm) in the posterior wall of the uterus that filled the endometrial cavity. The cut surface appeared tan with focal areas of hemorrhage ad necrosis. The ovaries , fallopian tubes and cervix were unremarkable
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Diagnosis & discussion |
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Case 7
Presented by: Dr. ME McMenamin
Clinical History
A 16-year-old Caucasian male underwent excsion of a’’ vascular tumour’’ of his left thumb nailbed following a two year history of local swelling. Glomus tumour with microscopic positive margins was diagnosed. Eleven years later, the patient was referred to the Plastic Surgery Department of a different hospital with presumed local recurrence, reporting a painful lesion of the distal left thumb of several months duration that showed dramatic growth and ulceration over the preceding weeks. Malignant transformation was suspected clinically and the provisional plan was amputation of distal thumb the subsequent week. Biopsies were performed ( H&E provided) and showed a malignant round cell tumour in the dermis with focal intraepidermal pagetoid spread.
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Diagnosis & discussion |
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Case 8
Presented by: Dr. B. Zelger
Clinical History
Tumor of a 6-year-old boy in the scrotal scar of a previous resection of paratesticular rhabdomyosarcoma.
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Diagnosis & discussion |
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