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Slide 5a1 |
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Slide 5a2 |
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Slide 5b |
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Slide 5c1 |
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Case 5
Presented by: Eva Honsova
Clinical History
A 19-year-old woman was admitted to the hospital for oliguric acute renal failure. The patient had been in excellent health until five weeks earlier, when she began to have respiratory symptoms with tonsilitis that was weakly responsive to antibiotics. During ATB therapy she suffered from nausea and vomiting, and one-day diarrhea. At the same time, she began to have mild arthralgias and weakness. The physical examination was normal except peripheral edema. There was no fever, lymphadenopathy or rush. No complaints of dysuria. Her blood pressure was 125/80 mm Hg. She took no chronic medication, except birth control pills during the previous year.
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Renal biopsy diagnosis: Thrombotic microangiopathy
Definitive diagnosis: Hemolytic uremic syndrome (HUS) with mutation in factor H and recurrence of the disease in the renal graft
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28.12.2007 |
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