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Case 4
Presented by: Laura Barisoni
Clinical History
An 18 month old patient presented with periorbital and lower extremities edema. At that time he had proteinuria > 10 g/day, serum cholesterol > 500 mg/dl and albumin < 1.5 g/dl. Serology was negative for Hepatitis B virus, Hepatitis C virus, EBV, HIV, and parvovirus B19. The patient’s parents are from Romania and non consanguineous. Parents and a brother are all healthy.
The patient was treated with Prednisone 2.3 mg/kg/day, diuretics and infusions of albumin. After four weeks of therapy, his edema increased and he developed anasarca. ACE inhibitors were added to the therapy and a renal biopsy was performed. Because of severe unremitting proteinuria, the patient underwent nephrectomy. Both, biopsy and nephrectomy specimens were sent in consultation and for additional studies to the Nephropathology Laboratory at NYU.
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Collapsing Glomerulopathy (CG), COQ2 NEPHROPATHY-ASSOCIATED
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28.12.2007 |
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