21st European Congress of Pathology Istanbul, Turkey, September 08-13, 2007 http://www.ecp2007istanbul.org/ Slide Seminar 13, September 10th Unexpected histological findings that change the clinical diagnosis in foetoplacental pathology
Chairpersons: P.B.Nunes and E.Ozer
Clinical History Mother aged 19 years primigravida. No consanguinity and no congenital abnormalities in the family. LMP 14/06/05, EDD by dates and by USS 21/03/06. No maternal diseases, in particular no hypertension or diabetes. Down’s screen test was normal. USS at 18+3 weeks and at 24+0 weeks showed fetal abnormalities: moderate cystic hygroma; right hydronephrosis; cardiac defect (double outlet right ventricle, transposition of the great arteries, ventricular septal defect) and possible ureterocele; polyhydramnios was also noted. CVS showed normal male karyotype. A mildly macerated hydropic male baby was spontaneously delivered at 30+2 weeks, BW 2620g (well above 99th centile).
Examination: Facial dysmorphism; skin flap on the neck.11 pairs of ribs. Bilateral pleural effusions; ascites; subcutaneous oedema; mild pulmonary hypoplasia. Heart: ASD; potential interventricular communication between muscular outlet septum and remainder of ventricular septum. Partial intestinal malrotation. Duplication of the right renal pelvis and ureter; segmental dysplasia of the upper pole of the right kidney; bilateral hydronephrosis and hydroureters. Testes looked normal and were sited in the abdominal cavity
ABNORMAL TESTICULAR HISTOLOGY AND RIGHT SEGMENTAL RENAL DYSPLASIA GTD
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