21st European Congress of Pathology Istanbul, Turkey, September 08-13, 2007 http://www.ecp2007istanbul.org/ Slide Seminar 13, September 10th Unexpected histological findings that change the clinical diagnosis in foetoplacental pathology
Chairpersons: P.B.Nunes and E.Ozer
Clinical History A 31 year old, gravida 3, para 2. Caucasian woman was referred to the tertiary fetal medicine unit at 18 weeks gestation because of a placental abnormality. Her previous pregnancies were unremarkable. An ultrasound scan showed generalized vesicular lesions affecting the whole placenta. There was a single fetus which demonstrated reduced growth parameters and oligohydramnios.
Macroscopic findings: The trimmed placental weight was 769 g (mean expected weight 451 g at 37 weeks gestation). The cord inserted eccentically and contained 3 vessels. The chorionic vessels were thickened and prominent. The cut surface was pale and friable with multiple cysts, measuring between 0.6 and 2 cm diameter, more frequently present on and beneath the material surface.
PLACENTAL MESENCHYMAL DYSPLASIA ASSOCIATED WITH KLINEFELTER SYNDROME (47,XXY)
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