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21st European Congress of Pathology
Istanbul, Turkey, September 08-13, 2007
http://www.ecp2007istanbul.org/
Slide Seminar 3, September 9th
Cytopathology
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Case 3
Presented by: Ziva Pohar Marinsek

Clinical History
A 48-years old female patient had a 3- month history of back pain which radiated into the abdomen. She was first treated wih analgetics and physiotherapy. When symptoms persisted a more thorugh investigation was undertaken. Laboratory tests disclosed normochromic anemia and thrombocytopenia, gynecologic examination and esophagoduodenoscopy were unremarcable. US examination revealed condensed liver parenhima with multiple round lesions, some of them cystic, measuring 2-3 cm. Similar lesions were also seen in the spleen. The patient was transferred to the Institute of Oncology where a CT scan was performed confirming the US examination and showing enlarged lymph nodes in the retroperitoneum. An US-guided FNAB was performed from one of the lesions in the liver. The cytologic diagnosis was angiosarcoma. A core needle biopsy was performed to confirm the diagnosis of the unusual tumor.

The patient´s condition deteriorated rapidly. She developed acute abdominal pain, jaundice, and ascitic fluid. Medrol and Taxol (50% of regular dose) were administered. She was seen a month afterwards in a slightly better condition but refused further chemotherapy. The patient has not returned the following month for the scedualed check up.


  
  Angiosarcoma of liver  
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28.12.2007
   


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