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21st European Congress of Pathology
Istanbul, Turkey, September 08-13, 2007
http://www.ecp2007istanbul.org/
Slide Seminar 5, September 10th
New and Controversial Entities of the New WHO Classification of Endocrine Tumors
Chairpersons: P. Komminoth (Switzerland), G. Rindi (Italy)

 

 

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Slide 4  
Case 4
Presented by: Prof. Sylvia Asa, Canada

Clinical History
This 36 year old woman had a thyroid nodule detected on her annual physical examination. She was asymptomatic and had no clinical features of hypo- or hyperthyroidism. Thyroid function tests were within the normal range and no anti-thyroid antibodies were identified. Ultrasound examination identified a 3 cm isoechoic nodule in the right lobe and needle aspiration biopsy was read as “thyroid follicular cells present”. The patient was sent for right thyroid lobectomy. The specimen consisted of a lobe of thyroid that measured 5cm SI x 4 cm ML x 3.2 cm AP. On section the mid-lobe contained a homogeneous tan to brown well-defined nodule that measured 3.2 cm SI x 3 cm ML x 2.5 cm AP. There was central cystic change and hemorrhage. The surrounding thyroid was grossly unremarkable.
  
  Diagnosis: Papillary carcinoma, oncocytic variant, with insular dedifferentiation: Thyroid (right lobectomy specimen)  
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28.12.2007
   


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