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21st European Congress of Pathology
Istanbul, Turkey, September 08-13, 2007
http://www.ecp2007istanbul.org/
Slide Seminar 8, September 12th
Challenging Cases in Gynecologic Pathology
Chairpersons: A. Giatromanolaki, E.Yavuz

 

 

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Slide 7  
Case 7
Presented by: David Hardisson

Clinical History
A 41-year-old woman, gravida 0, para 0, whose last menstrual period occurred two weeks before admission presented with vaginal bleeding. Previous medical history was unremarkable, and there was no history of prior radiation therapy or chemical exposures. Physical examination revealed an enlarged uterine corpus. Pelvic ultrasound showed a 10.1 x 9.2 cm uterine mass involving the posterior myometrial wall. The adnexae were normal. No free pelvic fluid was identified. The patient continued to bleed profusely, requiring surgical intervention. Total hysterectomy with bilateral salpingo-oophorectomy was performed without complication. There was no apparent extrauterine extension of tumor, although the serosal surface of the posterior uterine wall was interrupted by the tumor; lymph nodes were clinically unremarkable. The immediate postoperative course was uneventful. After the diagnosis the patient received chemotherapy and abdominal radiation therapy. Despite treatment, the patient developed multiple intraabdominal nodules consistent with local recurrence of the tumor 8 months following hysterectomy.
  
  PRIMARY OSTEOSARCOMA OF THE UTERUS  
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28.12.2007
   


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