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RENAL BIOPSY SLIDE SEMINAR March 17th, 2009
Department of Pathology
Tampere University Hospital
Heikki Helin

 

 

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Case 3  
Case 3
Female, 61 years.

Previously healthy female with oliguric renal failure. 15% plasma cells in bone marrow. High ESR, free IgG-lambda light chains in serum. Renal biopsy with following questions: myeloma cast nephropathy, multiple myeloma-associated AL-amyloidosis or light chain deposition disease?

Immunofluorescence: Brightly fluorescent lambda light chain casts in tubular lumina.
  
  Myeloma cast nephropathy 
 
 
 
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