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RENAL BIOPSY SLIDE SEMINAR March 17th, 2009
Department of Pathology
Tampere University Hospital
Heikki Helin
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Case 9
Female, 26 years.
SLE since the age of 6 years. Diffuse proliferative glomerulonephritis diagnosed in childhood. AIHA, phospholipid syndrome, blindness due to retinitis. Serum creatinine 63 ?mol/l, dU-prot 2.7 g, urinary RBC 7/HPF. Renal biopsy for nephritic syndrome: morphologic evidence of active lupus nephritis?
Immunofluorescence: Diffuse, granular, capillary IgG (++), IgA (++), IgM (++), C3 (++) and C1q (+++).
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SLE glomerulonephritis, class IV G, AC |
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